Prostate Cancer news | Breaking prostate cancer news | Prostate Cancer

Body, Heal Thyself

...Provenge is in a sense both personalized and general, says David L.

Urdal, Dendreon's chief scientific officer and vice chairman.

The personalized component comes from a blood sample taken from a patient in order to isolate dendritic cells, which deliver antigens to T-cells and B-cells, the lymphocytes that control the immune response.

Those dendritic cells are then cultured with the general component, prostatic acid phosphatase, a recombinant protein found in 95% of The dendritic cells, now loaded with the antigen, are then injected back into the patient to trigger a reaction from the immune system.

Patients receive three doses of the vaccine over the course of a month.

The method appears to be offering patients some hope.

The combined data from two Phase III trials in androgen-independent patients showed that the vaccine extended survival by four months, a 23% improvement over a placebo.

And just over twice as many patients given the vaccine (33%) compared with those given a placebo (15%) were still alive 36 months after treatment.

Dendreon has also completed enrollment in a Phase III trial in patients with the earlier stage and milder androgen-dependent "The idea is that Provenge would be most effective when the tumor burden is the smallest," Urdal notes.

There has also been evidence that administering the vaccine prior to chemotherapy rather than after it might be an effective sequence.

As the first player to ask FDA for...

Don’t build it ... and they won’t come

...Despite the sense of urgency, Burkey said he’s not sure he could stand before council and air his grievances.

“I am not a public speaker,” he said.

“To get up there and have them pop questions to me would make me damn mad.” Stevens said past city councils have indicated they would be willing to move more quickly on Burkey Park if the county agreed to split the cost of developing the property, but such an agreement has never materialized.

He also noted that the Burkey family, unlike the Long family, placed no conditions on a time frame for building the park.

When Dr.

William Long died in 2001, Mesa County inherited a 40-acre parcel on Patterson Road east of 31 Road.

Long’s will called for the land to be turned into a park by 2010, and the county has obliged, completing the first of four phases last fall.

But Palmer said he’s tired of the excuses.

“I’m embarrassed that we have this out there for 40 years, and if somebody doesn’t fight for it, it’s going to be another 20 years, and that’s just ridiculous,” Palmer said.

Stevens said there is something to salvage from the delay.

“From the Burkeys’ perspective, they were visionaries.

I’d say they were ahead of their time in donating the land to the city.

It’s just unfortunate that (39) years down the road, we still have a parcel of land,” he said.

“The good news is we still have land there, and if the ...

Patent application submitted regarding the mode of action for ...

...Active Biotech AB (corp.

reg.

no.

556223-9227) Box 724, 220 07 Lund Sweden Tel +46 (0) 46-19 20 00 Fax +46 (0) 46-19 20 50 Copyright © Hugin ASA 2006.

All rights reserved.

SOURCE: Active Biotech Back To Recent News Issuers of news releases, not Market Wire, are solely responsible for the accuracy of the content.

For more information about Market Wire's services, please Contact Us.

Site Map Copyright Market Wire ...

1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 | 39 | 40 | 41 | 42 | 43 | 44 | 45 | 46 | 47 | 48 | 49 | 50 | 51 | 52 | 53 | 54 | 55 | 56 | 57 | 58 | 59 | 60 | 61 | 62 | 63 | 64 | 65 | 66 | 67 | 68 | 69 | 70 | 71 | 72 | 73 | 74 | 75 | 76 | 77 | 78 | 79 | 80 | 81 | 82 | 83 | 84 | 85 | 86 | 87 | 88 | 89 | 90 | 91 | 92 | 93 | 94 | 95 | 96 | 97 | 98 | 99 | All news

Best Cancer Care