Prostate Cancer

...Mice that did not receive genistein in utero were much heavier as adults - double the weight of their genistein-fed counterparts.

Prenatal genistein also shifted the offspring's coat color from yellow to brown, demonstrating that a single nutrient can have a widespread systemic impact.Genistein's effect occurred early in pregnancy, the equivalent of eight gestational days in humans.

The Duke scientists said their results lend support to the "developmental origins of adult disease" hypothesis, in which an individual's long-term health is influenced by prenatal factors.Results of the study, funded by the National Institute of Environmental Health Sciences and the National Cancer Institute, appear in the April 1 issue of the journal Environmental Health Perspectives."We are increasingly finding that our parent's and even our grandparent's nutritional status and environmental exposures can regulate our future risk of disease," said Randy Jirtle, Ph.D., professor of radiation oncology and senior author of the study.

"In other words, it may not only be the hamburgers and fries we are eating, but also what our parents consumed or encountered in the environment that predisposes us to various conditions."Jirtle said a mechanism called DNA "methylation" is increasingly identified as the tri...

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Purchase Zone 3 Tower Ad Zone 4 Tower Ad Zone 5 Tower Ad Zone 6 Tower Ad President Bush, Meet Lorraine By Barbara Ehrenreich April 2006 Issue Here’s the news that rocked my little world this month: We got a message that a family friend, let’s call her Lorraine, who was in an ICU, barely able to breathe on her own.

In the last few weeks, there’d been some mumblings about “not feeling a hundred percent,” but no hint of anything seriously wrong.

The diagnosis came back in a couple of days: fourth-stage breast cancer, which has spread to a number of other organs, including her lungs.

If you know anything at all about breast cancer “staging,” you know there is no fifth stage.

Lorraine has no health insurance.

We didn’t know that.

In fact, we’d been content to believe that her consulting...

... New Gene That Causes Spread Of Cancer Identified, University Of Liverpool @import "css/default.css"; @import "css/defaultnews.css"; if (screen.width > 1000) document.write(''); 31st March 2006 home xml feeds newsletter advertise accessibility contact Archive Search Medical Abbreviations New Gene That Causes Spread Of Cancer Identified, University Of Liverpool This ArticleAlso Appears InGenetics Main Category: Cancer/Oncology News Article Date: 31 Mar 2006 - 0:00am (UK)Professor Philip Rudland, Dr Guozheng Wang and Dr Roger Barraclough from the University's Cancer and Polio Research Fund Laboratories have discovered an additional member of the S100 family of protein genes - S100P - that causes the spread of cancerous cells from an original tumour to other parts of the body.

If present in the primary tumour, metastagenes such as S100P trigger the rapid spread of cancerous secondary tumours to other tissues in the body via the bloodstream - a process known as metastasis.

Although primary tumours can be removed surgically, secondary tumours are more difficult to control.

This research has been funded by the Cancer and Polio Research Fund.

The new discovery builds on several years' work carried out at the University to investigate the genes that cause cancerous tumours to travel to other tissues in the body.

To date, three other metastasis-inducing genes have been discovered - S100A4, osteopontin, and more recently, AGR2.

Chemotherapy and radiotherapy are often the only optio...