Prostate Cancer

Usually patients undergo a prostate biopsy when they are found to have an elevated serum PSA.

About 10% of patients who undergo a prostate biopsy will be found to have high grade PIN.

Men with high grade PIN have an approximately 50 percent chance of progressing to In the United States, 1.1 million men have been diagnosed with high grade PIN, and it has been estimated that there are 14 million men who may unknowingly harbor the condition.

There are no medical treatments for high grade PIN.The Poster is scheduled to be presented Wednesday, April 5, 2006, 8 a.m.

- 12 p.m.

- Identification of ABCA5 as a tissue and urine diagnostic market for Prostatic Intraepithelial Neoplasia (PIN).

Abstract Number: 5163; Poster Section: 25; Board 7.

About GTxGTx is a biopharmaceutical company dedicated to the discovery, development and commercialization of therapeutics for cancer and serious conditions related to men's health.

GTx's lead drug discovery and development programs are focused on small molecules that selectively modulate the effects of estrogens and androgens, two essential classes of hormones.

GTx, headquartered in Memphis, Tenn., currently has four clinical programs.

GTx is developing ACAPODENE® (toremifene citrate), a selective estroge...

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