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Cancer Deaths Could be Reduced by Changes to Newly Found Gene

...This understanding of a common mechanism of cancer initiation could result in cancer prevention and in better assessment of cancer risk.

“We have a novel approach to cancer.

We know the initiating step,” said Dr.

Ercole Cavalieri of the Eppley Cancer Institute, University of Nebraska Medical Center.

“We think prevention of cancer is a problem we can solve by eliminating this initiating step.

Estrogens can induce cancer when natural mechanisms of protection do not work properly in our body, and the estrogen quinones are able to react with DNA.

In fact, if these protections are insufficient, due to genetic, lifestyle or environmental influences, then cancer can result.

“Now that we have the basic knowledge about a unifying mechanism of cancer initiation, we have a greater sense of urgency to assess people at risk and, at the same time, begin prevention by using specific natural compounds.” The study describes how the catechol estrogen quinones react with DNA to produce specific mutations that may trigger breast, prostate and other human cancers.

“We’ve known about these catechol estrogen quinones for a long time, through many different studies that we’ve done, but our most recent results hav...

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